Twenty-five years after the original series of murders in Woodsboro, a new killer emerges, and Sidney Prescott must return to uncover the truth.

After escaping an abusive husband, Anna and her 8-year-old son move to a secret location in a giant apartment building. Terrified that her ex-husband will find them, she buys a baby monitor to keep in her son's room at all times. But strange noises echo in the baby monitor from elsewhere in the building. As she witnesses the sounds of what she believes is another child being murdered, she fears it is her own.

An intriguing invitation brings six strangers together. Initially, they think they have gathered for a highly immersive escape room, but they soon make the sickening discovery that they are pawns in a sadistic game of life and death. Together, they move from one terrifying scenario to the next as they find clues and solve puzzles. But the players soon learn that exposing their darkest secrets may hold the key to survive.